Topic: openclaw
3,425 skills in this topic.
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bio-sam-bam-basics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-sashimi-plots
Creates sashimi plots showing RNA-seq read coverage and splice junction counts using ggsashimi or rmats2sashimiplot. Visualizes differential splicing events with grouped samples and junction read support. Use when visualizing specific splicing events or validating differential splicing results.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-seq-objects
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-data-io
Read, write, and create single-cell data objects using Seurat (R) and Scanpy (Python). Use for loading 10X Genomics data, importing/exporting h5ad and RDS files, creating Seurat objects and AnnData objects, and converting between formats. Use when loading, saving, or converting single-cell data formats.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-restriction-enzyme-selection
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-restriction-sites
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-ribo-seq-riboseq-preprocessing
Preprocess ribosome profiling data including adapter trimming, size selection, rRNA removal, and alignment. Use when preparing Ribo-seq reads for downstream analysis of translation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-small-rna-seq-mirge3-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-communication
Analyze cell-cell communication in spatial transcriptomics data using ligand-receptor analysis with Squidpy. Infer intercellular signaling, identify communication pathways, and visualize interaction networks. Use when analyzing cell-cell communication in spatial context.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-deconvolution
Estimate cell type composition in spatial transcriptomics spots using reference-based deconvolution. Use cell2location, RCTD, SPOTlight, or Tangram to infer cell type proportions from scRNA-seq references. Use when estimating cell type composition in spatial spots.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-phasing-imputation-genotype-imputation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-population-genetics-selection-statistics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-proteomics-differential-abundance
Statistical testing for differentially abundant proteins between conditions. Covers limma and MSstats workflows with multiple testing correction. Use when identifying proteins with significant abundance changes between experimental groups.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-proteomics-proteomics-qc
Quality control and assessment for proteomics data. Use when evaluating proteomics data quality before downstream analysis. Covers sample metrics, missing value patterns, replicate correlation, batch effects, and intensity distributions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-proteomics-quantification
Protein quantification from mass spectrometry data including label-free (LFQ, intensity-based), isobaric labeling (TMT, iTRAQ), and metabolic labeling (SILAC) approaches. Use when extracting protein abundances from MS data for differential analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-alignment-bwa-alignment
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-reporting-automated-qc-reports
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-metagenomics-strain-tracking
Track bacterial strains using MASH, sourmash, fastANI, and inStrain. Compare genomes, detect contamination, and monitor strain-level variation. Use when needing sub-species resolution for outbreak tracking, transmission analysis, or within-host strain dynamics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-methylation-based-detection
Analyzes cfDNA methylation patterns for cancer detection using cfMeDIP-seq or bisulfite sequencing with MethylDackel. Identifies cancer-specific methylation signatures and performs tissue-of-origin deconvolution. Use when using methylation biomarkers for early cancer detection or minimal residual disease.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-scatac-analysis
Single-cell ATAC-seq analysis with Signac (R/Seurat) and ArchR. Process 10X Genomics scATAC data, perform QC, dimensionality reduction, clustering, peak calling, and motif activity scoring with chromVAR. Use when analyzing single-cell ATAC-seq data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-tcr-bcr-analysis-mixcr-analysis
Perform V(D)J alignment and clonotype assembly from TCR-seq or BCR-seq data using MiXCR. Use when processing raw immune repertoire sequencing data to identify clonotypes and their frequencies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-cnv-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-gwas-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-variant-calling-deepvariant
Deep learning-based variant calling with Google DeepVariant. Provides high accuracy for germline SNPs and indels from Illumina, PacBio, and ONT data. Use when calling variants with DeepVariant deep learning caller.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009