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Topic: openclaw

3,425 skills in this topic.

bio-pathway-kegg-pathways KEGG pathway and module enrichment analysis using clusterProfiler enrichKEGG and enrichMKEGG. Use when identifying metabolic and signaling pathways over-represented in a gene list. Supports 4000+ organisms via KEGG online database.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-genome-intervals-interval-arithmetic
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-hi-c-analysis-hic-data-io Load, convert, and manipulate Hi-C contact matrices using cooler format. Read .cool/.mcool files, convert from .hic format, access matrix data, and export to different formats. Use when loading or converting Hi-C contact matrices.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-hi-c-analysis-loop-calling Detect chromatin loops and point interactions from Hi-C data using cooltools, chromosight, and HiCCUPS-like methods. Identify CTCF-mediated loops and enhancer-promoter contacts. Use when detecting chromatin loops from Hi-C data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-imaging-mass-cytometry-interactive-annotation Interactive cell type annotation for IMC data. Covers napari-based annotation, marker-guided labeling, training data generation, and annotation validation. Use when manually annotating cell types for training classifiers or validating automated phenotyping results.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-imaging-mass-cytometry-phenotyping Cell type assignment from marker expression in IMC data. Covers manual gating, clustering, and automated classification approaches. Use when assigning cell types to segmented IMC cells based on protein marker expression or when phenotyping cells in multiplexed imaging data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-immunoinformatics-mhc-binding-prediction Predict peptide-MHC class I and II binding affinity using MHCflurry and NetMHCpan neural network models. Identify potential T-cell epitopes from protein sequences. Use when predicting MHC binding for vaccine design or neoantigen identification.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-long-read-sequencing-nanopore-methylation Calls DNA methylation from Oxford Nanopore sequencing data using signal-level analysis. Use when detecting 5mC or 6mA modifications directly from nanopore reads without bisulfite conversion.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-longread-alignment Align long reads using minimap2 for Oxford Nanopore and PacBio data. Supports various presets for different read types and applications. Use when aligning ONT or PacBio reads to a reference genome for variant calling, SV detection, or coverage analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-genome-assembly-short-read-assembly
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-genome-engineering-grna-design Design guide RNAs for CRISPR-Cas9/Cas12a experiments using CRISPRscan and local scoring algorithms. Score guides for on-target activity using Rule Set 2 and Azimuth models. Use when designing sgRNAs for gene knockout, activation, or repression experiments.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-genome-engineering-off-target-prediction Predict CRISPR off-target sites using Cas-OFFinder and CFD scoring algorithms. Identify potential unintended cleavage sites genome-wide and assess guide specificity. Use when evaluating guide RNA specificity or selecting guides with minimal off-target risk.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-clinical-databases-pharmacogenomics Query PharmGKB and CPIC for drug-gene interactions, pharmacogenomic annotations, and dosing guidelines. Use when predicting drug response from genetic variants or implementing clinical pharmacogenomics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-chipseq-visualization Visualize ChIP-seq data using deepTools, Gviz, and ChIPseeker. Create heatmaps, profile plots, and genome browser tracks. Visualize signal around peaks, TSS, or custom regions. Use when visualizing ChIP-seq signal and peaks.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-clinical-databases-clinvar-lookup Query ClinVar for variant pathogenicity classifications, review status, and disease associations via REST API or local VCF. Use when determining clinical significance of variants for diagnostic or research purposes.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-data-visualization-interactive-visualization
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-copy-number-cnv-visualization Visualize copy number profiles, segments, and compare across samples. Create publication-quality plots of CNV data from CNVkit, GATK, or other callers. Use when creating genome-wide CNV plots, sample heatmaps, or chromosome-level visualizations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-crispr-screens-library-design CRISPR library design for genetic screens. Covers sgRNA selection, library composition, control design, and oligo ordering. Use when designing custom sgRNA libraries for knockout, activation, or interference screens.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-crispr-screens-mageck-analysis MAGeCK (Model-based Analysis of Genome-wide CRISPR-Cas9 Knockout) for pooled CRISPR screen analysis. Covers count normalization, gene ranking, and pathway analysis. Use when identifying essential genes, drug targets, or resistance mechanisms from dropout or enrichment screens.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-data-visualization-circos-plots
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-batch-downloads
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
arxiv-search Search arXiv physics, math, and computer science preprints using natural language queries. Powered by Valyu semantic search.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
benchling-integration Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-alignment-io Read, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO. Supports Clustal, PHYLIP, Stockholm, FASTA, Nexus, and other alignment formats for phylogenetics and conservation analysis. Use when reading, writing, or converting alignment file formats.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009