ReddRadar
Topic: nanoclaw
968 skills in this topic.
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bio-ribo-seq-translation-efficiency
Calculate translation efficiency (TE) as the ratio of ribosome occupancy to mRNA abundance. Use when comparing translational regulation between conditions or identifying genes with altered translation independent of transcription.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-sequence-slicing
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-similarity-searching
Performs molecular similarity searches using Tanimoto coefficient on fingerprints via RDKit. Finds structurally similar compounds using ECFP or MACCS keys and clusters molecules by structural similarity using Butina clustering. Use when finding analogs of a query compound or clustering chemical libraries.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-preprocessing
Quality control, filtering, and normalization for single-cell RNA-seq using Seurat (R) and Scanpy (Python). Use for calculating QC metrics, filtering cells and genes, normalizing counts, identifying highly variable genes, and scaling data. Use when filtering, normalizing, and selecting features in single-cell data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-splicing
Analyzes alternative splicing at single-cell resolution using BRIE2 for probabilistic PSI estimation or leafcutter2 for cluster-based analysis with NMD detection. Identifies cell-type-specific splicing patterns. Use when analyzing isoform usage in scRNA-seq or finding splicing differences between cell populations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-image-analysis
Process and analyze tissue images from spatial transcriptomics data using Squidpy. Extract image features, segment cells/nuclei, and compute morphological features from H&E or IF images. Use when processing tissue images for spatial transcriptomics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-preprocessing
Quality control, filtering, normalization, and feature selection for spatial transcriptomics data. Calculate QC metrics, filter spots/cells, normalize counts, and identify highly variable genes. Use when filtering and normalizing spatial transcriptomics data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-proteomics
Analyzes spatial proteomics data from CODEX, IMC, and MIBI platforms including cell segmentation and protein colocalization. Use when working with multiplexed imaging data, analyzing protein spatial patterns, or integrating spatial proteomics with transcriptomics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-sra-data
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-substructure-search
Searches molecular libraries for substructure matches using SMARTS patterns with RDKit. Filters compounds by pharmacophore features, functional groups, or scaffold matches with atom mapping. Use when finding compounds containing specific chemical moieties or filtering libraries by structural features.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-systems-biology-flux-balance-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-tumor-fraction-estimation
Estimates circulating tumor DNA fraction from shallow whole-genome sequencing using ichorCNA. Detects copy number alterations via HMM segmentation and calculates ctDNA percentage. Requires 0.1-1x sWGS coverage. Use when quantifying tumor burden from liquid biopsy or monitoring treatment response.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-variant-calling
Call SNPs and indels from aligned reads using bcftools mpileup and call. Use when detecting variants from BAM files or generating VCF from alignments.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-vcf-manipulation
Merge, concatenate, sort, intersect, and subset VCF files using bcftools. Use when combining variant files, comparing call sets, or restructuring VCF data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-biomarker-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-chipseq-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-crispr-screen-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-hic-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-imc-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-longread-sv-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-metabolomics-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-neoantigen-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-spatial-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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biomedical-data-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009