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Topic: awesome

1,258 skills in this topic.

bio-gatk-variant-calling Variant calling with GATK HaplotypeCaller following best practices. Covers germline SNP/indel calling, GVCF workflow for cohorts, joint genotyping, and variant quality score recalibration (VQSR). Use when calling variants with GATK HaplotypeCaller.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-fragment-analysis Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin. Extracts nucleosome positioning patterns, fragment ratios, and DELFI-style fragmentation profiles for cancer detection. Use when leveraging fragment patterns for tumor detection or tissue-of-origin analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
claims-appeals
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
labstep Interact with the Labstep electronic lab notebook API using labstepPy. Query experiments, protocols, resources, inventory, and other lab entities.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
scientific-manuscript
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
boltzgen All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration. For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use boltz.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
immune-checkpoint-combination-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
drug-discovery-search End-to-end drug discovery platform combining ChEMBL compounds, DrugBank, targets, and FDA labels. Natural language powered by Valyu.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-fastq-quality Work with FASTQ quality scores using Biopython. Use when analyzing read quality, filtering by quality, trimming low-quality bases, or generating quality reports.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
neurokit2 Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements. Applicable for heart rate variability analysis, event-related potentials, complexity measures, autonomic nervous system assessment, psychophysiology research, and multi-modal physiological signal integration.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-filter-sequences Filter and select sequences by criteria (length, ID, GC content, patterns) using Biopython. Use when subsetting sequences, removing unwanted records, or selecting by specific criteria.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-flow-cytometry-gating-analysis Manual and automated gating for defining cell populations in flow cytometry. Covers rectangular, polygon, and data-driven gates. Use when identifying cell populations through hierarchical gating strategies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-flow-cytometry-clustering-phenotyping Unsupervised clustering and cell type identification for flow/mass cytometry. Covers FlowSOM, Phenograph, and CATALYST workflows. Use when discovering cell populations in high-dimensional cytometry data without predefined gates.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-flow-cytometry-cytometry-qc Comprehensive quality control for flow cytometry and CyTOF data. Covers flow rate stability, signal drift, margin events, dead cell exclusion, and batch QC. Use when assessing acquisition quality or identifying problematic samples before analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
chembl-search Search ChEMBL bioactive molecules database with natural language queries. Find compounds and assay data with Valyu semantic search.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
myeloma-mrd-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-spatial-transcriptomics Analyze spatial transcriptomics data to map gene expression in tissue architecture. Supports 10x Visium, MERFISH, seqFISH, Slide-seq, and imaging-based platforms. Performs spatial clustering, domain identification, cell-cell proximity analysis, spatial gene expression patterns, tissue architecture mapping, and integration with single-cell data. Use when analyzing spatial transcriptomics datasets, studying tissue organization, identifying spatial expression patterns, mapping cell-cell interactions in tissue context, characterizing tumor microenvironment spatial structure, or integrating spatial and single-cell RNA-seq data for comprehensive tissue analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
convergence-study Spatial and temporal convergence analysis with Richardson extrapolation and Grid Convergence Index (GCI) for solution verification
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-splicing Analyzes alternative splicing at single-cell resolution using BRIE2 for probabilistic PSI estimation or leafcutter2 for cluster-based analysis with NMD detection. Identifies cell-type-specific splicing patterns. Use when analyzing isoform usage in scRNA-seq or finding splicing differences between cell populations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
arboreto Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-imc-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-neoantigen-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-spatial-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
matchms Mass spectrometry analysis. Process mzML/MGF/MSP, spectral similarity (cosine, modified cosine), metadata harmonization, compound ID, for metabolomics and MS data processing.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009